Timed Fault Tree Models of the China Yongwen Railway Accident

Safety is an essential requirement for railway transportation. There are many methods that have been developed to predict, prevent and mitigate accidents in this context. All of these methods have their own purpose and limitations. This paper presents a new useful analysis technique: timed fault tree analysis. This method extends traditional fault tree analysis with temporal events and fault characteristics. Timed Fault Trees (TFTs) can determine which faults need to be eliminated urgently, and it can also provide a safe time window to repair them. They can also be used to determine the time taken for railway maintenance requirements, and thereby improve maintenance efficiency, and reduce risks. In this paper, we present the features and functionality of a railway transportation system based on timed fault tree models. We demonstrate the applicability of our framework via a case study of the China Yongwen line railway accident

Availability analysis of satellite positioning systems for aviation using the prism model checker

This paper highlights an application of probabilistic model checking to satellite positioning systems for aircraft guidance. After introducing our formal approach based on using the PRISM model checker, we built a model of a global navigation satellite system (GNSS) based positioning system for a specific flight in the probabilistic π-calculus, a process algebra which supports modelling of concurrency, uncertainty, and mobility. After that, we encode our model into the PRISM language. We then analyse the availability properties that relate to the dependability and overall performance of the underlying system. The aim of our research is to use PRISM to assist industrial designers and developers of the GNSS

Formal specification and quantitative analysis of a constellation of navigation satellites

Navigation satellites are a core component of navigation satellite-based systems such as Global Positioning System, Global Navigation Satellite System and Galileo, which provide location and timing information for a variety of uses. Such satellites are designed for operating on orbit to perform tasks and have lifetimes of 10  years or more. Reliability, availability and maintainability analysis of systems has been indispensable in the design phase of satellites in order to achieve minimum failures or to increase mean time between failures and thus to plan maintenance strategies, optimise reliability and maximise availability. In this paper, we present formal models of both a single satellite and a navigation satellite constellation and logical specification of their reliability, availability and maintainability properties, respectively. The probabilistic model checker PRISM has been used to perform automated analysis of these quantitative properties

Risk assessment of railway transportation systems using timed fault trees

Safety is an essential requirement for railway transportation. There are many methods that have been developed to predict, prevent, and mitigate accidents in this context. All of these methods have their own purpose and limitations. This paper presents a new useful analysis technique: timed fault tree analysis. This method extends traditional fault tree analysis with temporal events and fault characteristics. Timed fault trees (TFTs) can determine which faults need to be eliminated urgently, and it can also provide how much time have been left at least to eliminate the root failure to prevent accidents. They can also be used to determine the time taken for railway maintenance requirements, and thereby improve maintenance efficiency, and reduce risks. In this paper, we present the features and functionality of a railway transportation system, and principles and rules of TFTs. We demonstrate the applicability of our framework by a case study on a simple railway transportation system

Products of absolute retracts

TIB: RN 2394 (897) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Mechanistic insight into the adverse outcome of tire wear and road particle leachate exposure in zebrafish (Danio rerio) larvae

Tire wear particles (TWP) have become the major microplastic pollution in China. Road runoff containing TWP leachate can decrease the eye size and even induced mortality in the aquatic organisms. However, the toxic mechanism of TWP and road particles (RP) leachate on aquatic organisms is still unclear. In this study, the zebrafish embryos were exposed to TWP or RP leachate for 5 days at both environmental relevant and high concentrations. The adverse outcome pathways (AOPs) were screened from individual to molecular levels. The morphological and behavioral analysis demonstrated that the leachate exposure mainly impaired the eye development of zebrafish larvae and inhibited the larval swim behavior and phototactic response, which are the adverse outcomes. The phototransduction modulated by zebrafish retina was significantly down-regulated through transcriptomics and metabolomics analysis. The eye histopathological analysis showed that the decreased thickness of the retinal outer nuclear layer (ONL) and retinal pigmented epithelium (RPE) after leachate exposure were caused by the decreased photoreceptor cells. Moreover, the expression of NR2E3 and TPO genes showed concentration-dependent down-regulation after leachate exposure. The inhibition of photoreceptor cell proliferation was identified as the main reason for photoreceptor cell decrease in zebrafish larval eye. This study, for the first time, uncovered the underlying toxic mechanism of TWP and RP on zebrafish larval eyes